Facilities
For data housing and analysis, the BIRC lab contains a high capacity (12 terabyte) storage system as well as 12 multi-processor Linux data analysis workstations, all of which reside on a gigabit ethernet network. The lab also houses a 9-node Beowulf computing cluster capable of over 64 teraflops of processing throughput. Available MR scanners for functional neuroimaging include a 3 T GE Excite scanner and a 3 T Philips Achieva system. The latter resides at the McKnight Brain Institute.
Brain Imaging Rehabilitation and Cognition Lab
Parkinson Aphasia Paper - Individual ROI correlations
Active Grants and Projects
Crosson, B. (PI) Career Research Scientist Award. Funded through the Department of Veterans Affairs Rehabilitation Research and Development Service. 2004-2008.
Crosson, B. (PI) Treatment of Intention in Aphasia: Neural Substrates. R01-DC007387: funded through the National Institutes of Health. National Institute on Deafness and Other Communication Disorders. 2006-2009.
Rothi, L. J. G. (Center Director). Veterans Affairs RR&D Brain Rehabilitation Center. Funded through the Department of Veterans Affairs. 2004-2009.
Neuroplasticity in upper extremity rehabilitation
Neuroplasticity in lower extremity rehabilitation
Crosson, B. (PI). Hemispheric Asymmetry Reduction in OLD Adults during Word Generation. Funded through the Evelyn F. McKnight Brain Research Grant Program.
Tim W. Conway, Ph.D. (PI). Reliability and Variability of fMRI of Language in Aphasic Adults. Department of Veterans Affairs, Rehabilitation Research and Development. Associate Investigator Award (full salary and benefits). 2003-2005.David B. FitzGerald, M.D. (PI). Memory Plasticity in the Elderly. Department of Veterans Affairs, Rehabilitation Research and Development and Evelyn F. McKnight Brain Research Grant Program. Associate Investigator Award (full salary and benefits). 2006-2008.
Recent Publications
- Crosson, B., Ford, A., McGregor, K.M., Meinzer, M., Briggs, R. (in press) Functional Imaging and Related Techniques: A Brief Introduction for Rehabilitation Researchers. Journal of Rehabilitation Research and Development
- Trinastic, J., Kautz, S., McGregor, K., Gregory, C.,Bowden, M., Benjamin, M., Kleim, J., Kurtzman, M., Chang, Y., Conway, T., Crosson, B. (in press) An fMRI study of differences in brain activity during active ankle dorsiflexion and plantarflexion. Brain Imaging and Behavior Epub 2010 Feb 10.
- Crosson, B. , Moore, A., McGregor, K.M., Chang. YL., Benjamin, M.,Gopinath, K., Sherod, M.G., Wierenga, C.E., Peck, K., Briggs, R.W., Gonzalez Rothi, L., White, K.D. (2009) Regional Changes in Word-Production Laterality After a Naming Treatment Designed to Produce a Rightward Shift in Frontal Activity. Brain and Language. 111(2): 73-85.
- McGregor, K.M., Benjamin, M., Craggs, J., Crosson, B.,White,. K.D. (2009) Hand Movement Evokes Age-related Changes in Motor Control During Unimanual Movements. Brain Imaging and Behavior. 3(4): 317-331.
- Brain reorganizes during training after stroke B Crosson et al. Journal of Cognitive Neuroscience 17, 392-406 (2005).
- Role of the basal ganglia in language and semantics: Supporting cast Crosson, B., Benjamin, M., Levy, I. (2008). In J. Hart, Jr. & M Kraut (eds.), Neural Basis of Semantic Memory. New York: Cambridge.
- Treatment of naming in nonfluent aphasia through manipulation of intention and attention: A phase 1 comparison of two novel treatments B Crosson et al. Journal of the International Neuropsychological Society 13, 582-594. (2007).
- Age-related changes in word retrieval: Role of bilateral frontal and subcortical networks C Wierenga et al. (in press). Neurobiology of aging. (2006).
- Functional MRI of Language in Aphasia: A Review of the Literature and the Methodological Challenges Crosson, B., McGregor, K. et al. Neuropsychology Review 17: 157-177 (2007).
- Treatment of word-finding deficits in fluent aphasia through the manipulation of spatial attention: Preliminary findings Dotson, V., Singletary, F., Fuller, R., Koehler, S., Moore, A.B., Gonzalez Rothi, L., Crosson, B. Aphasiology, 22 (1), 103-113 (2008).
- Discriminating brain activity from task-related artifacts in functional MRI: Fractal scaling analysis simulation and application Lee, J., Hu, J., Gao, J., Crosson, B., Peck, K., Wierenga, C., McGregor, K., Zhao, Q., White, K. (In Press) NeuroImage (2008).
INS Conference posters 2008
- "Age Group Comparisons in Category Member Generation Tasks: Effect of Stimulus Design" Keith M. McGregor, Michelle L. Benjamin, Yu-Ling Chang, Zvinka Zlatar, Colin Rackelman, Megan Gaiefsky, Ilana Levy, Keith D. White, and Bruce Crosson
- "Hemispheric Asymmetry Reductions in Older Adults during Category Exemplar Generation" Michelle L. Benjamin, Keith M. McGregor, Yu-Ling Chang, Keith D. White, Colin Rackelman, Megan Sherod, Ilana Levy, and Bruce Crosson
CNS Conference posters 2006
- "Negative BOLD and Aging: An fMRI study" K.M. McGregor, K.D. White, M. Benjamin, W.K. Berg, I. Fischler, J. Craggs, B. Crosson.
- "Changes in Activation of Neural Substrates in Two Patiets with Agrammatic Aphasia After Syntactic Mapping Treatment" T. Perez, A. Orynich, A. Wabnitz, K.M. McGregor, K.D. White, A.B. Moore, L.M. Maher, K.K. Peck, C.E. Wierenga, K. Gopinath, M. Kurtzman, M. Gaiefsky, M. Benjamin, D.A. Soltysik, R. Briggs, B. Crosson.
INS Conference posters 2006
- "Compensatory Reorganization in Recovery from Aphasia after Stroke" Bruce Crosson
- "Time Courses of fMRI Activations Spanning The Stimulus-Response Interval During Word Generation By Nonfluent Aphasics" C.A. Orynich, T. Perez, A. Wabnitz, A.B. Moore, B. Crosson, K. McGregor, K. Gopinath, C.E. Wierenga, M.E. Gaiefsky, K.K. Peck, R.W. Briggs, T.W. Conway, L.J. Gonzalez Rothi, K.D. White.
- "An fMRI Investigation of Sentence Generation Attempts by Chronic Non-fluent Aphasics" K.M. McGregor, K.D. White, A.B. Moore, L.M. Maher, K.K. Peck, C.W. Wierenga, K. Gopinath, M. Kurtzman, M. Gaiefsky, A. Wabnitz, M. Benjamin, D.A. Soltysik, R. Briggs, B. Crosson.
- "Self-Perception of Language Performance Following Stroke" M.E. Gaiefsky, A.B. Moore, L.J. Gonzalez-Rothi, M. Marsiske, M. Diehl, B. Crosson.
- "Lesion Pattern and Rehabilitative Treatment Success in Aphasia: Voxel-Based vs. Lesion Rating Techniques" M.A. Cato, C.E. Wierenga, R.B. Parkinson, Y.-L. Chang, B. Crosson.
- "Lesion Characteristics Related to Naming Improvement in Aphasic Stroke Patients: The Role of Anterior Cortex and the Basal Ganglia" R.B. Parkinson, Y.-L. Chang, A.M. Raymer, B. Crosson.
- "BOLD fMRI Reveals Neural Reorganization of Overt Pseudoword Repetition Following Phonological-Motor Treatment of Phonological Alexia in Nonfluent Aphasia" Y.L. Chang, T. Conway, D. Kendall, K. McGregor, K. Gopinath, K.K. Peck, M. Benjamin, M. Kurtzman, M. Gaiefsky, A. Wabnitz, T. Perez, L.J. Gonzalez Rothi, K.D. White, B. Crosson